Author/Authors :
Dehghani، Farideh نويسنده Department of Dermatology, Shahid Sadooghi University of Medical Sciences, Yazd, Iran. Dehghani, Farideh , Ebrahimzadeh، Mohammad نويسنده Department of Biology, Islamic Azad University, Varamin Branch, Varamin, Iran , , Moghimi، Mansour نويسنده Department of pathology, Shahid Sadoughi University of medical sciences and health services, Yazd, Iran , , Noorbala، Mohammad Taghi نويسنده Department of Dermatology, School of Medicinen, Shahid Sadoughi University of Medical Sciences, Yazd, IR Iran ,
Abstract :
Amyloidosis cutis dyschromica (ACD) is a rare form of macular amyloidosis characterized by hypo and hyperpigmented macules. Here we described a 20 year old girl with diffuse hypo and hyperpigmentation since she was four years old. Five other members of her family are also involved. Biopsy of hyperpigmented lesions revealed increase of melanin in the basal layer, pigment incontinence and amorphous eosinophilic masses stained positive with Congo red in the papillary dermis. The histopathologic findings were consistent with amyloidosis cutis dyschromica. Other investigations were normal. Dermatologists should consider amyloidosis cutis dyschromica when visit a patient with diffuse hypo and hyperpigmentation.
