Author/Authors :
Salehi-Vaziri، Mostafa نويسنده Department of Virology, Institute Pasteur of Iran, Tehran,
IR Iran , , Sadeghi، Farzin نويسنده Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, IR Iran , , Bokharaei-Salim، Farah نويسنده Department of Virology, School of Medicine, Iran
University of Medical Sciences, Tehran, IR Iran , , Younesi، Sarang نويسنده Department of Clinical Laboratory Sciences, Nilou Medical
Laboratory, Tehran, IR Iran , , Alinaghi، Samaneh نويسنده Department of Cellular and Molecular Biology, Tonekabon
Branch, Islamic Azad University, Tonekabon, IR Iran , , Monavari، Seyed Hamidreza نويسنده PhD, Associate professor, Department of Virology and Anti-Microbial Resistance Research Center , , Keyvani، Hossein نويسنده ,
Abstract :
Human papillomavirus (HPV) is the most common viral sexually-transmitted infection. Despite HPV infection is associated with several malignant disorders including penile and anal cancers, little is known about the epidemiology of HPV infection in males, particularly in developing countries. The aim of this study was to determine the prevalence of HPV infection and its genotype distribution among Iranian males. Between March 2009 and April 2014, a total number of 483 males, referred to Iran University of Medical Sciences-affiliated sexually transmitted infections (STI) clinics, were enrolled in this study. Following DNA extraction, HPV detection and genotyping were performed using INNO-LiPA HPV Genotyping Extra assay. To analyze the association of HPV infection and age, the logistic regression was employed. No statistical association between HPV infection and age was observed (P = 0.469). Furthermore, there was no statistically significant correlation between HR HPV infection and age (P = 0.330). In this investigation, the prevalence of HPV infection was relatively substantial. Totally, 17 different HPV genotypes were detected and the most frequently detected genotypes were HPV6, HPV11, HPV16, HPV18 and HPV52, respectively. The data from this study is essential for planning future public health strategies including HPV vaccination programs
