Title of article :
Choriocarcinoma metastatic to the kidney in amenorrheic woman following normal vaginal delivery
Author/Authors :
Behnamfar، Fariba نويسنده Associate professor, Department of Obstetrics and Gynecology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran Behnamfar, Fariba , Mohammadizadeh، Fereshteh نويسنده , , Hashemi، Leila نويسنده Department of Obstetrics and Gynecology, Shahid Beheshti Hospital, Isfahan University of Medical Sciences, Isfahan, Iran , , Sheikhalian، Somayeh نويسنده Resident of Obstetrics and Gynecology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran Sheikhalian, Somayeh
Issue Information :
فصلنامه با شماره پیاپی 0 سال 2014
Pages :
5
From page :
33
To page :
37
Abstract :

Gestational choriocarcinoma usually occurs following an intrauterine pregnancy. We report a case of metastatic choriocarcinoma to the left kidney and lungs with long term intermittent amenorrhea and vaginal bleeding after a normal vaginal delivery. A 43 year old rural woman presented with three years intermittent amenorrhea and vaginal bleeding following normal vaginal delivery. She also complained of gross hematuria and left flank pain and had a rising titer of serum β- hCG. Pathologic examination of endometrial curettage specimen revealed choriocarcinoma. Ultrasound revealed enlarged uterus involved by an irregular mass with heterogenous echo pattern and extensive myometrial invasion. A mass with similar echo pattern was also evident in the left kidney.Computerized tomography confirmed the intrauterine mass and involvement of the left kidney. On chest X ray, metastatic nodules were seen in both lungs and in the left retrocardiac space. The patient underwent chemotherapy with EMA-CO regimen (etoposide, methotrexate, actinomycin D, cyclophosphamide, and vincristine/oncovine). During chemotherapy, she became pancytopenic and febrile. This condition was successfully managed with G-CSF, leukovorin and antibiotics. The patient is now well and still under the chemotherapy. Her serum β- hCG level has fell to 6 IU/ml.

Journal title :
Basic and Clinical Cancer Research
Serial Year :
2014
Journal title :
Basic and Clinical Cancer Research
Record number :
2387837
Link To Document :
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