Author/Authors :
Atalay، Eray نويسنده Department of Internal Medicine, Kafkas University Practice and Research Hospital, Kars, Turkey Atalay, Eray , ?zdemir، Mehmet Tamer نويسنده Department of Internal Medicine, Kafkas University Practice and Research Hospital, Kars, Turkey ?zdemir, Mehmet Tamer , Ci?sar، Gül?en نويسنده Kafkas University Practice and Reserch Hospital Emergency Department Kars, Turkey Ci?sar, Gül?en , Omurca، Ferhat نويسنده Department of Internal Medicine, Kafkas University Practice and Research Hospital, Kars, Turkey Omurca, Ferhat , Aslan، Nurullah نويسنده Department of Internal Medicine, Kafkas University Practice and Research Hospital, Kars, Turkey Aslan, Nurullah , Yildiz، Mehmet نويسنده Department of Internal Medicine, Kafkas University Practice and Research Hospital, Kars, Turkey Yildiz, Mehmet , Gey، Zehra Bahar نويسنده Medical University of Pleven, Faculty of Medicine Pleven, Bulgaria Gey, Zehra Bahar
Abstract :
Angioedema is an asymmetric non-pitting oedema on face, lips, tongue and mucous membranes; any delay in diagnosis and treatment can be fatal. Treatment with lisinopril as an angiotensin converting enzyme (ACE) inhibitor, can be a reason of angioedema. Here we report a case who developed oral-facial edema four years after using lisinopril/hydrochlorothiazide. Laryngeal oedema is a main cause of death in angioedema. The treatment of choice in angioedema including fresh frozen plasma, C1 inhibitor concentrations and BRK-2 antagonists (bradykinin B2 receptor antagonists) were used. In this case; a 77 years old female patient suffering from hypertension was considered. This patient was suffering two days from swelling on her face and neck. Non- allergic angioedema was distinguished in five major forms; acquired (AAO), hereditary (HAE), renin-angiotensin-aldosterone system (RAAS) blocker-dependent, pseudoallergic angioedema (PAS) and an idiopathic angioedema (IAO). She was admitted to our clinic with the diagnosis of hereditary angioedema. Patient had skin edema and life threatening laryngeal edema. In emergency department treatment was started using intravenous methylprednisolone, diphenydramine as well as inhaled and subcutaneous epinephrine simultaneously. Despite the initial treatment, the patient died due to the insufficient respiration and cardiac arrest. The patient has no history of kidney disease.
