Author/Authors :
Moghimi، Mansour نويسنده Department of pathology, Shahid Sadoughi University of medical sciences and health services, Yazd, Iran , , Yazdian-Anari، Pouria نويسنده medical student, Yazd Student Research Committee, Shahid Sadoughi University of Medical Sciences, Yazd, Iran , , Vaghefi، Marzie نويسنده Medical Student Research Committee, Shahid Sadoughi
University of Medical Sciences, Yazd, Iran , , Meidany، Abbas نويسنده Medical Student Research Committee, Shahid Sadoughi
University of Medical Sciences, Yazd, Iran , , Salehi، Heidar نويسنده Medical Student Research Committee, Shahid Sadoughi
University of Medical Sciences, Yazd, Iran ,
Abstract :
Nodular fasciitis of the breast is a rare benign pathology of soft
tissue that is a consequence of fibroblastic hyperplasia within breast.
It can mimic breast cancer clinically, radiologically, and
histopathologically. A-43 year-old female with a painless mass within
upper-lateral quadrant of her left breast complained of rapid and
progressive growth during previous few days. No evidence of nipple
discharge or sensation of pain was expressed. The mass was tender to
palpation, but the size was too tiny to detect. The definitive diagnosis
was established with sonography, which detected a hypoechogenic lesion,
10 mm in diameter. The excisional biopsy delivered a tissue composed of
fusiform fibroblastic cells with bright ellipsoid-like nuclei and
elevated nucleolus. Mitotic formations were also obvious. Low cellular
and high cellular zones with hyaline fibrosis and erythrocyte
accumulation existed, as well as a light lymphocytic infiltration. All
of these features, in addition to adipocytic accumulation within the
margins of this lesion, suggested a definitive diagnosis of Nodular
fasciitis. The diagnosis of nodular fasciitis is difficult and often is
indiscriminable from breast cancer, so paying close attention to this
matter is critical.
