Author/Authors :
Khajeh ، Ali نويسنده Assistant Professor of Pediatric Neurology, Research Center for Children and Adolescents Health (RCCAH), Zahedan University of Medical Sciences, Zahed , , Miri-Aliabad، Ghasem نويسنده Department of Pediatrics, Children and Adolescent Health Research Center, Zahedan University of Medical Sciences, Zahedan, Iran Miri-Aliabad, Ghasem , Fayyazi، Afshin نويسنده MD,Pediatric Neurologist, Assistant Professor of Hamedan University of Medical Sciences, Hamadan, Iran , , Safdari، Zohreh نويسنده Zahedan University of Medical Sciences, Zahedan, IR
Iran , , Keikha، Maryam نويسنده Zahedan University of Medical Sciences, Zahedan, IR
Iran , , Askari، Hassan نويسنده Department of Nursing, Pregnancy Health Research Center,
Zahedan University of Medical Sciences, Zahedan, IR
Iran ,
Abstract :
Background Febrile seizures (FS) are the most common form of
convulsion in children with the aged between 6 months to 5 years.
Different studies have shown that reduction of zinc leads to the
incidence of FS in children. Objectives This study was conducted with
the goal of examination of the zinc level in the patients with FS.
Patients and Methods This case-control study was conducted on 90
children in three equal groups of children with febrile seizures,
febrile children without febrile seizures (FS) and healthy children. In
order to examine the zinc level blood samples were taken of all subjects
and the zinc level of these patients was determined. The data was
analyzed using the SPSS-16 statistical software and by descriptive
statistical tests and ANOVA. Results Forty three male (47.2%) and 47
female children (52.8%) with the average age of 2.43 ± 1.23 years were
examined. The three groups had no significant difference in terms of age
and sex. The average of zinc level in the patients with FS was 56.8 ±
52.7 µg/dL and it was 96.1 ± 53.4 µg/dL in the febrile children without
FS and 108 ± 28 µg/dL in the healthy control group. According to ANOVA
test, there was a significant difference between the three groups in
terms of the zinc level (P = 0.01). Conclusions The low serum zinc level
in the group of patients with FS compared with two other groups can
indicate the existence of a relationship between the serum zinc level
and development of FS in children aged between 6 months and 5 years.
