Title of article :
Paraoxonase (PON1) 55 polymorphism and association with systemic lupus erythematosus.
Author/Authors :
Bahrehmand، Fariborz نويسنده Molecular Diagnostic Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran. Bahrehmand, Fariborz , Vaisi-Raygani، Asad نويسنده Dept. of Clinical Biochemistry, Kermanshah University of Medical Sciences, Kermanshah, Iran Vaisi-Raygani, Asad , Ahmadi، Reza نويسنده Specialist in infection diseases, 22-Bahman Hospi-tal , , Kiani، Amir نويسنده Ph.D. Candidate at Earthquake Risk Management Research Center, IIEES Kiani, Amir , Rahimi، Zohreh نويسنده , , Tavilani، Heidar نويسنده Department of Biochemistry, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran. , , Pourmotabbed، Tayebeh نويسنده Department of Microbiology, Immunology and Biochemistry, University of Tennessee, Health Science Center, Tennessee, USA. Pourmotabbed, Tayebeh
Issue Information :
فصلنامه با شماره پیاپی 0 سال 2013
Pages :
9
From page :
211
To page :
219
Abstract :
Paraoxonase-1 (PON1) is a serum HDL-bound enzyme that hydrolyzes a number of aromatic carboxylic acid esters including lipid peroxides, preventing LDL oxidation. Systemic lupus erythematosus (SLE) patients are at greater risk of oxidative stress, which is associated with abnormal plasma lipid metabolism. In this study, association of PON-55 polymorphism with serum arylesterase (ARE) activities, malondialdehyde (MDA), neopterin, lipids and lipoproteins levels in SLE patients and the development of hypertension was investigated. The present case-control study consisted of 109 SLE patients with and without high blood pressure (BP) and 103 healthy controls from the population in the west of Iran. PON-55 Met
Journal title :
Iranian Journal of Allergy, Asthma and Immunology
Serial Year :
2013
Journal title :
Iranian Journal of Allergy, Asthma and Immunology
Record number :
2389230
Link To Document :
