Author/Authors :
Su?rez-Varela، Mar?a Morales نويسنده Unit of Public Health, Hygiene, and Environmental Care, Department of Preventive Medicine, University of Valencia, Valencia, Spain AND CIBER Epidemiology and Public Health (CIBERESP), Spain AND Center for Public Health Research (CSISP), Valencia, Spain Su?rez-Varela, Mar?a Morales , Gallardo-Juan، Amparo نويسنده Section of Radiology, General Hospital, Valencia. Spain Gallardo-Juan, Amparo , Garc?a-Marcos، Lu?s نويسنده Pediatric Respiratory Medicine and Allergy Units, Virgen de la Arrixaca University Childrens Hospital, University of Murcia, Spain Garc?a-Marcos, Lu?s , Gimeno-Clemente، Natalia نويسنده CIBER Epidemiology and Public Health (CIBERESP), Spain AND Unit of Public Health and Environmental Care, Department of Preventive Medicine, University of Valencia, Valencia, Spain Gimeno-Clemente, Natalia , Silvarrey-Varela، Angel L?pez نويسنده Foundation Mar?a José Jove, A Coru?a, Spain Silvarrey-Varela, Angel L?pez , Miner-Canflanca، I?aqui نويسنده Department of Paediatrics, Hospital de Donostia, San Sebasti?n, Spain Miner-Canflanca, I?aqui , Batlles-Garrido، José نويسنده Department of Paediatrics, Hospital Torrec?rdenas, Almer?a, Spain Batlles-Garrido, José , Blanco-Quiros، Alfredo نويسنده Department of Paediatrics, University of Valladolid, Valladolid, Spain Blanco-Quiros, Alfredo , Busquets-Monge، Rosa Mar?a نويسنده Department of Paediatrics, Hospital del Mar, Barcelona, Spain Busquets-Monge, Rosa Mar?a , Dom?nguez-Aurrecoechea، Bego?a نويسنده Health Centre of Otero, Oviedo, Spain Dom?nguez-Aurrecoechea, Bego?a , Arnedo-Pena، Alberto نويسنده Section of Epidemiology, Centre of Public Health, Regional Ministry of Health, Castell?n, Spain Arnedo-Pena, Alberto , Gonz?lez-D?az، Carlos نويسنده Unit of Paediatric Allergy, Department of Paediatrics, Hospital of Basurto, Bilbao, Spain Gonz?lez-D?az, Carlos , Aguinaga-Ontoso، Inés نويسنده Department of Health Sciences, Public University of Navarra, Navarra, Spain Aguinaga-Ontoso, Inés , Mart?nez-Gimeno، Antonio نويسنده Department of Pediatrics, "Santa Luc?a" University Hospital, Cartagena, Spain Mart?nez-Gimeno, Antonio , Llopis-Gonz?lez، Agust?n نويسنده Unit of Public Health, Hygiene, and Environmental Care, Department of Preventive Medicine, University of Valencia, Valencia, Spain AND CIBER Epidemiology and Public Health (CIBERESP), Spain AND Center for Public Health Research (CSISP), Valencia, Spain Llopis-Gonz?lez, Agust?n
Abstract :
Atopic Eczema (AE) is a chronic inflammatory skin disease that affects children and adults, and alters quality of life with a high morbidity rate and severe economic burden. The objective of the present work was to analyse specific atmospheric pollutants (O3, NO, PM10 and SO2) affecting the prevalence of diagnosed AE and its symptoms among 6-7-year-old schoolchildren.
The participants included 21311 schoolchildren aged 6-7 years from 8 Spanish regions, whose parents completed the ISAAC Phase III questionnaire to ascertain AE diagnosis and symptoms. The mean levels (µg/m3) of O3, NO, PM10 (particles 10 micrometers or less in diameter) and SO2 were determined in each geographical area participating in this study.
According to these mean levels, three levels of exposure to each pollutant were considered: level 1 (percentiles 0-25); level 2 (percentiles 26-74); level 3 (percentiles 75-100). Exposure to O3 was associated with increased prevalence of rashes (exposure level 2, Odds Ratio (OR): 1.22, 95% Confidence Interval (95%CI): 1.02-1.45; level 3 OR: 1.33, 95%CI:1.10-1.61) and diagnosed AE (level 2, OR: 1.27, 95%CI: 1.17-1.39; level 3 OR: 1.27, 95%CI:1.15-1.41). An association was found between the level of NO and a drop in the prevalence of diagnosed AE (exposure level 2, OR: 0.88, 95%CI: 0.81-0.95; level 3 OR: 0.85, 95%CI:0.74-0.97). There was also an association between the highest exposure level to PM10 and a reduced prevalence of rashes (level 3 OR: 0.42, 95%CI: 0.22-0.81) and diagnosed AE (level 3OR: 0.53, 95%CI: 0.38-0.75).
Future studies into exposure to O3 and its relationship with allergic diseases may be conducted in order to prevent this association.
