Author/Authors :
Salehi Sadaghiani، Mohammad نويسنده Research Center for Immunodeficiency, Pediatrics Center of Excellence, Childrens Medical Center, Tehran University of Medical Sciences, Tehran, Iran Salehi Sadaghiani, Mohammad , Aghamohammadi، Asghar نويسنده , , Ashrafi، Mahmoud-Reza نويسنده Department of Pediatrics, Children’s Medical Center,
School of Medicine, Tehran University of Medical Sciences, Tehran,
IR Iran , , Hosseini، Firozeh نويسنده Department of Pediatric Neurology, Hamadan University of Medical Sciences, Hamadan, Iran. Hosseini, Firozeh , Abolhassani، Hassan نويسنده , , Rezaei، Nima نويسنده ,
Abstract :
Autism is a neurodevelopmental disorder, characterized by poor social interaction and communication impairment and repetitive behavior. Autism is considered as a genetic and multifactorial disorder, with diverse risk factors involved.
Herein, we report a 13-year-old male with common variable immunodeficiency (CVID), who was diagnosed with autism at the age of 3 years old.
As there are some evidences about the role of the immune system defects in the pathogenesis of autism, specific primary antibody deficiency diseases such as CVID might predispose some affected cases to this neurodevelopmental disorders.