Author/Authors :
Dalili، Setila نويسنده Pediatrics Growth Disorders Research Center, School of Medicine, Guilan University of Medical Sciences, Rasht, IR Iran , , Rezvany، Seyed Mahmood نويسنده Guilan Health Center, Guilan University of Medical Sciences, Guilan, Iran. Rezvany, Seyed Mahmood , Dadashi، Arsalan نويسنده Guilan Health Center, Guilan University of Medical Sciences, Guilan, Iran. Dadashi, Arsalan , Medghalchi، Abdolreza نويسنده Eye Research Center, Amiralmomenin Hospital, Faculty of Medicine, Guilan University of Medical Sciences, Guilan , Iran. Medghalchi, Abdolreza , Mohammadi، Hamid نويسنده Assistant Professor, University of Zabol. , , Dalili، Hosein نويسنده Breast feeding Research Center, Tehran University of Medical Sciences, Tehran, Iran Dalili, Hosein , Mirzanejad، Mostafa نويسنده Guilan Health Center, Guilan University of Medical Sciences, Guilan, Iran. Mirzanejad, Mostafa , Gholamnezhad، Hajar نويسنده Health Center, Guilan University of Medical Sciences, Guilan, Iran. Gholamnezhad, Hajar , Amirhakimi، Anis نويسنده Division of Pediatric Cardiology, Department of Pediatric, Shiraz University of Medical Sciences, Shiraz, IR Iran ,
Abstract :
This study was aimed to evaluate the situation of congenital hypothyroidism (CH) in Guilan using the screening program and determine the correlation of CH with birth weight, gestational age and seasonality. During 2006 to 2010, in Guilan province, neonatal screening for CH by measurement of serum TSH level was performed in 3-5 days after birth. All neonates with TSH level ≥ 5mu/l were referred to endocrinologists and serum TSH, T3 and T4 were measured. Based on public health data and profiles, total number of newborns, gestational age, route of delivery, birth season and birth weight in all screened neonates was reviewed and for ones with CH, their TSH measurements was also recorded. During 5 years, 119701 neonates were screened and CH was confirmed in 10.8% (221) of the referral cases (prevalence=1:542). No significant statistical difference was seen between gender and birth season among patients with CH and the rest of the population. Interestingly, low birth weight (LBW) (31% vs. 4.9%, P
