Author/Authors :
Nayeri، Fatemeh نويسنده Family Health Institute, Maternal- Fetal & Neonatal Research Center, Tehran University of Medical Sciences, Tehran, Iran. Nayeri, Fatemeh , Dalili، Hosein نويسنده Breast feeding Research Center, Tehran University of Medical Sciences, Tehran, Iran Dalili, Hosein , Nili، Firoozeh نويسنده 1 Breast feeding Research Center, Tehran University of Medical Science, Tehran, Iran.2 Fetal & Neona Nili, Firoozeh , Amini، Elaheh نويسنده , , Ardehali، Ali نويسنده General Physician, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Ardehali, Ali , Khoshkrood Mansoori، Babak نويسنده General Physician, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Khoshkrood Mansoori, Babak , Shariat، Mamak نويسنده ,
Abstract :
The objective of this study is to determine risk factors causing increase in very low birth way (VLBW) neonatal mortality. The medical files of all neonates weighing ≤1500 g, born in Vali-e-Asr hospital (2001-2004) were studied. Two groups of neonates (living and dead) were compared up to the time of hospital discharge or death. A total of 317 neonates were enrolled. A meaningful relationship existed between occurrence of death and low gestational age (P=0.02), low birth weight, lower than 1000 g (P=0.001), Apgar score <6 at 5th minutes (P=0.001), resuscitation at birth (P=0.001), respiratory distress syndrome (P=0.001) need for mechanical ventilation (P=0.001), neurological complications (P=0.001) and intraventricular hemorrhage (P=0.001). Regression analysis indicated that each 250 g weight increase up to 1250 g had protective effect, and reduced mortality rate. The causes of death of those neonates weighting over 1250 g should be sought in factors other than weight. Survival rate was calculated to be 80.4% for neonates weighing more than 1000 g. The most important high risk factors affecting mortality of neonates are: low birth weight, need for resuscitation at birth, need for ventilator use and intraventricular hemorrhage.