Author/Authors :
Abtahi، Naeimeh Sadat نويسنده Department of Embryology, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran , , Ebrahimi، Bita نويسنده Department of Embryology at Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran , , Fathi، Rouhollah نويسنده Department of Embryology at Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran , , Khodaverdi، Sepideh نويسنده Endometriosis Research Center, Iran University of Medical Science, Tehran, Iran , , Mehdizadeh Kashi، Abolfazl نويسنده Endometriosis Research Center, Iran University of Medical Science, Tehran, Iran , , Rezazadeh Valojerdi، Mojtaba نويسنده ,
Abstract :
From December 2000 until 2010, the researchers at Royan Institute conducted a wide range
of investigations on ovarian tissue cryopreservation with the intent to provide fertility preservation
to cancer patients that were considered to be candidates for these services. In 2010,
Royan Institute established the Royan Human Ovarian Tissue Bank as a subgroup of the
Embryology Department. Since its inception, approximately 180 patients between the ages
of 7- 47 years have undergone consultations. Ovarian samples were cryopreserved from 47
patients (age: 7-35 years) diagnosed with cervical adenocarcinoma (n=9); breast carcinoma
(n=7), Ewing’s sarcoma (n=7), opposite side ovarian tumor (n=7), endometrial adenocarcinoma
(n=4), malignant colon tumors (n=3), as well as Hodgkin’s lymphoma, major thalassemia
and acute lymphoblastic leukemia (n=1-2 patients for each disease). Additionally,
two patients requested ovarian tissue transplantation after completion of their treatments.
