Pituitary Function Impairment after Moderate Traumatic Brain Injury
Hadji Abadi، Mohammad Reza نويسنده Department of Neurosurgery, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Hadji Abadi, Mohammad Reza , Ghodsi، Seyed Mohammad نويسنده Brain and Spinal Cord Injury Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran Ghodsi, Seyed Mohammad , Merazin، Masoud نويسنده Department of Neurosurgery, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Merazin, Masoud , Roozbeh، Hadi نويسنده Department of Neurosurgery, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Roozbeh, Hadi
To determine the prevalence of pituitary hormone deficiencies after moderate traumatic brain injury (TBI). We conducted a prospective cohort and included 75 patients with moderate TBI with GCS between 9 and 13 who referred to emergency department of Shariati Hospital, Tehran/Iran, during 2004-2007. Pituitary hormones were assessed 3 and 6 months after injury. In 3rd month post-injury, 39 cases had not any pituitary dysfunction; however, deficiencies in one, two and three of the pituitary hormones were found in 26, 8 and 2 patients, respectively. Twenty one patients showed a deficiency in one of the pituitary hormones and only one case with deficiency of two after 6 months. The most prevalent changes occur in IGF-1 and LH/FSH after moderate TBI. However, the whole deficiencies decrease over the time.