Author/Authors :
Shahraki Zahedani، Shahram نويسنده Department of Microbiology, School of Medicine, Zahedan University of Medical Sciences, Zahedan, IR Iran , , Moghadampour، Mehdi نويسنده Department of Microbiology, School of Medicine, Zahedan University of Medical Sciences, Zahedan, IR Iran , , Bokaeian، Mohammad نويسنده , , Ansari-Moghaddam، Alireza نويسنده Department of Epidemiology and Biostatistics, Health Promotion Research Center, Faculty of Health, Zahedan University of Medical Sciences, Zahedan Ansari-Moghaddam, Alireza
Abstract :
Background
Extended-spectrum beta-lactamases (ESBLs) represents a significant and rapid emerging problem around the world. Nowadays, antibiotic resistance determinants are prevalent in both hospital and community strains of Gram-negative enteric bacteria.
Materials and Methods
In this sectional-descriptive study, 87 clinical isolates of Klebsiella pneumoniae were collected from outpatients and their susceptibility to antimicrobial agents, minimum inhibitory concentration (MIC) values for third-generation cephalosporins and ESBLs production were assessed.
Results
Of 87 K. pneumoniae clinical isolates, 20 (22.9%) isolates represented the ESBLs phenotype.
Conclusions
Our results demonstrated that the resistance to the third-generation cephalosporins in K. pneumoniae strains isolated from outpatients is relatively high in Zahedan.
