A Novel Approach to Determine Dosage in Treatment of AIDS Based on Direct Self Tuning Regulator (STR) Theory and Linearization Around Equilibrium Condition

One of the main problems related to AIDS, is lack of control, lack of identification and early treatment of this disease. Today physicians more than anything, control the disease relying on their experience and knowledge and time-consuming and complex experiments, nevertheless, human errors are inevitable. In this study, a new approach for control (treatment) of AIDS based on patient entry drug is proposed. This paper investigated AIDS’s dynamic model such that couple inputs (RTI1 and PI2) have been simplified by one input and finally by using linearization around operating point, the dynamic model linearized only with one input. Finally, by applying control signal to the disease by using direct adaptive control (STR 3), the disease can be controlled adaptively as the patientʹs condition is not worse and controlled. The proposed system by combining these methods waiting for dynamic attribute in terms of composition and interaction to high matching accuracy is able to reach small amounts and a substantial sum of squared errors SSE4, mean absolute error and mean square error MAE5 MSE6. The present methods, despite on high precision, are time-consuming and expensive. By comparing this method and those methods, we will discover accuracy and efficiency of these methods.