Author/Authors :
Goudarzi، Hossein نويسنده Shahid Beheshti University of Medical Sciences , , Taherpour، Arezou نويسنده Department of Microbiology, Kurdistan University of Medical Sciences, Taherpour, Arezou , Fallah، Fatemeh نويسنده , , Pourkaveh، Bita نويسنده Infectious Disease and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences. Pourkaveh, Bita , Erfanimanesh، Soroor نويسنده Department of Microbiology, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Erfanimanesh, Soroor , Hashemi، Ali نويسنده Shahid Beheshti University of Medical Sciences ,
Abstract :
The nosocomial infections, caused by multi-drug resistant bacteria, are the most important cause of mortality throughout the world. One important mechanism against beta-lactam antibiotics is the production of beta-lactamases. Enterobacteriaceae and non-fermentative bacteria, like Pseudomonas aeruginosa and Acinetobacter baumannnii may produce these enzymes. Currently, there is no vaccine to prevent the infections caused by β-lactamase-producing bacteria. Consequently, it is necessary to identify β-lactamase-producing bacteria by phenotypic and molecular methods.