Author/Authors :
Niroumand، Shabnam نويسنده Department of Community Medicine, School of Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran , , Dadgarmoghaddam، Maliheh نويسنده School of Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran , , Bakhshayesh-Eghbali، Babak نويسنده Department of Neurology, Poursina Hospital, Guilan University of Medical Sciences, Rasht, Iran , , Abrishami، Maryam نويسنده Iranian National Center of Laser Science and Technology, Tehran, Iran , , Gholoobi، Arash نويسنده Atherosclerosis Prevention Research Center, Imam Reza Hospital, Mashhad, Iran. , , Bahrami Taghanaki، Hamid Reza نويسنده Department of Traditional Chinese Medicine, Faculty of Traditional Iranian Medicine, Mashhad University of Medical Sciences, Mashhad, Iran Correspondence:Seyyed Ali Mozaffarpur, Babol University of Medical , , Khajedaluee، Mohammad نويسنده ,
Abstract :
Diabetes mellitus is assumed to be a strong risk factor for cardiovascular diseases (CVD) and is frequently associated with other CVD risk factors. The aims of this study were to assess the prevalence of different patterns of dyslipidemia in individuals with diabetes compared with non-diabetic subjects and evaluate other accompanied CVD risk factors between the two groups. This was an analytical cross-sectional study on 230 participants, aged 28 - 66 years old, who were referred to different urban health centers of Khorasan Razavi province (north-east of Iran). Data from the participants were collected during their first visit by primary care physicians. Statistical package for social science (version 11.5) was used to analyze the data. The chi-square or Fisher’s exact, student’s t or the Mann-Whitney U and correlation tests were used in the analysis. The age and gender of the participants were not different between the two groups (P = 0.1 and P = 0.4, respectively). The most common patterns of dyslipidemia in both groups were isolated dyslipidemia followed by combined dyslipidemia. Prevalence of dyslipidemia as a whole (one, two or three lipid profile abnormalities) in patients with diabetes and non-diabetic participants was 89.3% and 82.6%, respectively and the difference between the two groups was not statistically significant (P = 0.1). Subjects with diabetes had higher systolic blood pressure (P < 0.001), higher diastolic blood pressure (P = 0.002) and higher body mass index (P = 0.09) compared to non-diabetics. Moreover, they were more likely to have higher levels of total cholesterol (P = 0.01), triglycerides (P = 0.001) and low density lipoprotein cholesterol (P = 0.009) and lower levels of high density lipoprotein cholesterol (P = 0.2). Cardiovascular diseases risk factors are more common in patients with diabetes; however, non-diabetic individuals also had a high prevalence of risk factors in our region, predisposing them to diabetes. Therefore, further attention by the medical community is necessary to choose effective strategies for a more a aggressive approach to prevent and manage these risk factors.
