Antimicrobial activity of tetraacetylethylenediamine-sodium perborate versus sodium hypochlorite against Enterococcus faecalis

Background. This study evaluated the antimicrobial activity of Tetraacetylethylenediaminesodium perborate (TAEDSP) in comparison to 2.5% and 5% sodium hypochlorite (NaOCl) against Enterococcus faecalis.Methods.A standard suspension of E. faecalis was inoculated on 60 plates containing MuellerHinton agar culture medium. Four sterile disks of Beckman filtration paper were placed on each plate. TAEDSP, 5% and 2.5% NaOCl were placed on three disks. Sterile physiologic saline was placed on the fourth disk as negative control. After 24hour incubation, the diameter of the inhibition zone around the disks was measured using a transparent ruler. Oneway Analysis of Variance (ANOVA) was used to compare the mean zone of microbial growth in the groups. Pvalues less than 0.05 were considered statistically significant.Results. There was a significant difference in the diameter of the inhibition zones between groups (P < 0.05). The Tukey post hoc test showed a higher diameter of the inhibitory zone with TAEDSP than that of 2.5% NaOCl. However, there were no significant differences between the inhibitory zones of TAEDSP and 5% NaOCl.Conclusion. TAEDSP and 5% NaOCl have similar antibacterial activity against E. faecalis however, TAEDSP has a greater antibacterial effect compared to 2.5% NaOCl.