Antimicrobial Susceptibility Pattern of Pseudomonas aeruginosa Isolated from Patients Referring to Hospitals

Please cite this article as: Golshani Z, Ahadi AM, Sharifzadeh A. Antimicrobial Susceptibility Pattern of Pseudomonas aeruginosa Isolated from Patients Referring to Hospitals. Arch Hyg Sci 2012;1(2):48-53. Abstract: Background & Aims of the Study: The aim of this study was to detect and survey the antibiotic resistance pattern of Pseudomonas (P.) aeruginosa isolated from patients in Isfahan (located in central Iran) hospitals. Materials & Methods : A Total of 50 clinical isolates of P. aeruginosa were collected from urine, wound, trachea, ear swab, and pus, and then were confirmed by standard tests. Antibiotic susceptibility was determined by the Kirby-Bauer disc diffusion method. Susceptibility data were compared by chi-square test using SPSS version 15. Results: Among the isolated strains, resistance to oxacillin was seen in 100%, ceftriaxone in 76%, amikacin in 70%, ceftazidime in 68%, cefepime in 68%, tobramycin in 62%, gentamicin in 60%, ciprofloxacin in 58%, and imipenem in 58% of the isolates. Conclusions: Comparison of the results showed that, patterns of antibiotic resistance are different from one hospital to another in various areas. Therefore, it is suggested that such studies should be performed in different hospitals. Also, prescribing correct medications is essential to prevent further increases in resistant bacteria. References: 1. Pagani L, Mantengoli E, Migliavacca R, Nucleo E, Pollini S, Spalla M, et al. Multifocal Detection of Multidrug-Resistant Pseudomonas aeruginosa Producing the PER-1 Extended- Spectrum β-Lactamase in Northern Italy. J Clin Microbiol 2004;42(6):2523–9. 2. Ling TKW, Xiong J, Yu Y, Lee CC, Ye H, Hawkey PM, et al. 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