Author/Authors :
Aurich، Stefanie نويسنده Department of Dermatology, Venereology and Allergology, University Hospital, Leipzig, Germany Aurich, Stefanie , Seitz، Anna-Theresa نويسنده Department of Dermatology, Venereology and Allergology, University Hospital, Leipzig, Germany Seitz, Anna-Theresa , Tomm، Janina نويسنده Department of Dermatology, Venereology and Allergology, University Hospital, Leipzig, Germany AND Helmholtz Centre for Environmental Research, Leipzig, Germany Tomm, Janina , Simon، Jan-Christoph نويسنده Department of Dermatology, Venereology and Allergology, University Hospital, Leipzig, Germany Simon, Jan-Christoph , Treudler، Regina نويسنده Department of Dermatology, Venereology and Allergology, University Hospital, Leipzig, Germany Treudler, Regina
Abstract :
In medicine, patent blue violet (PBV) is utilized for staining lymphatic vessels in sentinel lymph node (SLN) surgery. Moreover, PBV (also called E131 ) is used as food additive. We report on a 51-year-old non-atopic female with early breast cancer, who was scheduled for SLN excision and experienced an intra-operative anaphylactic reaction. In diagnostics the skin prick test (SPT) was positive to PBV. Hypersensitivity reactions to PBV can arise after the first exposure in surgery as sensitization may arise from either PBV (E131) in foods (i.e. in sweets or blue curacao) or from other structurally closely related triarylmethane dyes in objects of everyday life like textiles, detergents, paints, cold remedies and cosmetics. This article supports the necessity of an increased awareness of the possibility of anaphylactic reactions to PBV during SLN surgery, even if the patient never had contact to PBV before.
