Author/Authors :
Salarian، Sara نويسنده Anesthesiology Research Center,Shahid Beheshti University of Medical Sciences,Tehran,Iran , , Taherkhanchi، Bahar نويسنده School of Medicine,Department of Pediatric,Semnan University of Medical Sciences,Semnan,Iran , , Dabbagh، Ali نويسنده Professor, Fellowship in Cardiac Anesthesiology, Anesthesiology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran , , Darban، Mahboubeh نويسنده Kowsar Hospital,Department of Internal Medicine,Semnan University of Medical Sciences,Semnan,Iran , , Bagheri، Bahador نويسنده Cancer Research Center,Department of Pharmacology,Semnan University of Medical Sciences,Semnan,Iran ,
Abstract :
Dexmedetomidine (PRECEDEX) is an imidazole derivative that is a highly selective a2 receptor agonist. Activation of the a2 adrenergic receptors by dexmedetomidine leads to both sedation and analgesia; with negligible respiratory and cardiovascular side effects. The drug is likely to be increasingly used for sedation and as an anesthetic adjunct.