Author/Authors :
NASEHI، Mohammad Mehdi نويسنده Pediatric Neurology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. , , Sahraian، Mohammad Ali نويسنده , , Naser Moghadasi، Abdorreza نويسنده Headache Research Center, Iranian Center of Neurological Research, Neuroscience Institute AND Department of Neurology, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran Naser Moghadasi, Abdorreza , GHOFRANI، Mohammad نويسنده Pediatric Neurology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. , , ASHTARI، FERESHTEH نويسنده , , TAGHDIRI، Mohammad Mahdi نويسنده Pediatric Neurology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran , , Tonekaboni، Seyed Hassan نويسنده , , Karimzadeh، Parvaneh نويسنده , , AFSHARI، Mahdi نويسنده Department of Community Medicine, Zabol University of Medical Sciences, Zabol, Iran. , , MOOSAZADEH، Mahmood نويسنده Health Sciences Research Center, Faculty of Health, Mazandaran University of Medical Sciences, Sari, Iran. ,
Abstract :
Abstract
Objective
Overall, 2%-5% of patients with multiple sclerosis (MS) experienced the first episode of disease before the age 18 years old. Since the age of onset among children is not similar to that in general population, clinicians often fail to early diagnose the disease. This study aimed to determine the epidemiological and clinical patterns of MS among Iranian children.
Materials & Methods
In this cross-sectional study carried out in Iran in 2014-2015, information was collected using a checklist with approved reliability and validity. Method sampling was consensus. Data were analyzed using frequency, mean and standard deviation indices by means of SPSS ver. 20 software.
Results
Totally, 177 MS children were investigated. 75.7% of them were female. Mean (SD), minimum and maximum age of subjects were 15.9 (2), 7 and 18 yr, respectively. The most reported symptoms were sensory (28.2%), motor (29.4%), diplopia (20.3%) and visual (32.8%). Primary MRI results showed 91.5% and 53.1% periventricular and spinal cord lesions, respectively.
Conclusion
MS is significantly more common among women. The most common age of onset is during the second decades. Sensory and motor problems are the most symptoms, while, periventricular and spinal cord lesions are the most MRI results.
