Author/Authors :
Fahimzad ، Alireza نويسنده , , Eydian ، Zahra نويسنده , , Karimi ، Abdollah نويسنده , , Shiva ، Farideh نويسنده , , Sayyahfar ، Shirin نويسنده , , Kahbazi، Manijeh نويسنده , , Rahbarimanesh ، Aliakbar نويسنده , , Sedighi ، Iraj نويسنده , , Arjmand ، Reza نويسنده , , Soleimani ، Gholamreza نويسنده , , Sanaei Dasht، Anahita نويسنده , , Abdinia ، Babak نويسنده , , Mostafavi ، Nasser نويسنده , , Nikfar ، Roya نويسنده , , Abedini ، Masomeh نويسنده , , Rezaei، Mohammad Sadegh نويسنده , , Mohammadpour، Ali نويسنده , , Hashemian ، Houman نويسنده , , Hidari ، Hossein نويسنده , , Ghadiri ، Keyghobad نويسنده , , Entezari Heravi، Reza نويسنده ,
Abstract :
BACKGROUND: Antibiotics are among the most commonly prescribed drugs in pediatrics. Due to lack of uniformity in pediatric antimicrobial prescribing and the emergence of antibiotic resistance, appropriate drug utilization studies have been found to be crucial to evaluate whether these drugs are properly used.
METHODS: Data were collected between January 2014 and February 2014 in 16 Iranian pediatric hospitals using a standardized method. The point prevalence survey included all inpatient beds.
RESULTS: Of 858 children, 571 (66.6%) received one or more antimicrobials. The indications were therapeutic in 60.6%. The parenteral route was used in 92.5% of therapeutic indications. Ceftriaxone was the most prescribed antimicrobials for therapeutic indications (32.4%) and combination-therapy was the most type of therapy in pediatric intelligent care unit (PICU).
CONCLUSION: According to results of this study, antibiotics’ prescribing in pediatrics wards of Iranian hospitals is empirical. Therefore, for quality improvement of antimicrobial use in children continuous audit process and antibiotic prescriptions require further investigation.
Keywords :
antibiotic , Point prevalence , Prophylaxis , Targeted therapy , empiric therapy