Title of article
Presence of the Helicobacter pylori in Esophageal Squamous Cell Carcinoma Sample
Author/Authors
Khademian، Aynaz نويسنده 1MSc Student in Medical Microbiology, Students Research Committee, Babol University of Medical Sciences, Babol, Iran , , RAJABNIA، Ramazan نويسنده Babul University of Medical Sciences,Department of microbiology , , Ferdosi Shahandashti، Elaheh نويسنده Babul University of Medical Sciences, , , Khafri، Soraya نويسنده Department of Biostatistics and Epidemiology, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran , , Shokri-Shirvani، Javad نويسنده Department of Gastroenterology, Babol University of Medical Sciences, Ayatollah Rouhani Hospital, Babol, Iran , , Sadeghi، Farzin نويسنده Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, IR Iran , , Yahyapour، Yousef نويسنده Infectious Disease and Tropical Center, Babol University of Medical Sciences, Babol, IR Iran ,
Issue Information
فصلنامه با شماره پیاپی 0 سال 2016
Pages
5
From page
1
To page
5
Abstract
Background: The main causes of esophageal squamous cell carcinoma (ESCC) in developing countries differ from developed countries. In developing countries, approximately one-fourth of cancer cases are caused by infectious agents. In terms of infectious etiology of esophageal cancer, Helicobacter pylori has been among the most widely investigated, but its role in etiology of ESCC remains unclear.
Objectives: The present study aimed to investigate the presence of H. pylori in the pathogenesis of ESCC.
Materials and Methods: In total, 277 formalin-fixed paraffin-embedded esophageal samples (177 with ESCC, and 107 without esophageal malignancy) were examined for H. pylori infection. After removing of paraffin from tissue samples, DNA was extracted and polymerase chain reaction (PCR) was performed to investigate the presence of H.pylori.
Results: H. pylori was not detected in any of the cancerous and non-cancerous esophageal sample.
Journal title
International Journal of Enteric Pathogens
Serial Year
2016
Journal title
International Journal of Enteric Pathogens
Record number
2403880
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