Title of article :
One-step three-component and solvent-free synthesis of thiazoles from tertiary thioamides
Author/Authors :
Zali-Boeini, Hassan Department of Chemistry - Faculty of Science - University of Isfahan , Mansouri, Gholamhossein Department of Chemistry - Faculty of Science - University of Isfahan
Abstract :
A novel one-pot three-component reaction has been developed for construction of thiazole derivatives under solvent-free conditions. Hence, tertiary thioamides, α-haloketones, and NH4OAc were grinded together and allowed to react thermally at 110 °C and/or under microwave irradiation to produce the corresponding thiazole derivatives in very good yields.
Keywords :
Synthetic methods , Sulfur heterocycles , Thiazole , Green chemistry
Journal title :
Astroparticle Physics
