Title of article :
Novel synthesis of 1,4-benzothiazines in water accelerated by β-cyclodextrin
Author/Authors :
Londhe, Balaji S Department of Chemistry - Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, India , Padwal, Sudhakar L Department of Chemistry - Karmaveer Bhaurao Patil Mahavidyalaya, Pandharpur, India , Bhosale, Manisha R Department of Chemistry - Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, India , Mane, Ramrao A Department of Chemistry - Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, India
Abstract :
Novel one-pot synthetic protocol has been developed for obtaining 2, 3-disubstituted 1,4-benzothiazines with excellent yields, carrying cyclocondensation of 1,3-dicarbonyl compounds with substituted 2-(2-(2-aminophenyl)disulfanyl)benzenamines, under supramolecular catalysis of β-Cyclodextrin (β-CD) in water at neutral pH. The role of β-CD in accelerating the cyclocondensation has been demonstrated. This biomimic catalyzed route is simple, economic, relatively rapid and environmentally benign.
Keywords :
1,4-Benzothiazines , Supramolecular catalyst , β-Cyclodextrin , Biomimetic catalysis
Journal title :
Astroparticle Physics
