Author/Authors :
Taheri, Salman Laboratory of Organic Synthesis and Natural Products - Chemistry and Chemical Engineering Research Center of Iran,Tehran, Iran , Mohammadi, Ali Asghar Laboratory of Organic Synthesis and Natural Products - Chemistry and Chemical Engineering Research Center of Iran,Tehran, Iran , Ahdenov, Reza Laboratory of Organic Synthesis and Natural Products - Chemistry and Chemical Engineering Research Center of Iran,Tehran, Iran , Azarlak, Robab Laboratory of Organic Synthesis and Natural Products - Chemistry and Chemical Engineering Research Center of Iran,Tehran, Iran
Abstract :
An efficient one-pot synthesis of fused dihydrothiopyrano[2,3-b]indole-3-carbonitriles has been developed through ultrasound mediated reaction by simply combining malononitrile and various aldehydes with two indoline-2(3H)-thiones. The method has the advantages of high yields, short reaction time, good functional group tolerance and green reaction conditions.
Keywords :
Dihydrothiopyrano[2,3-b] indole-3-carbonitriles , Indoline-2(3H)thiones , Ultrasound irradiation