Title of article
N-Boc Protection of Amines Using Silica Propyl(N-methyl) Imidazolium Chloride as an Efficient and Reusable Catalyst
Author/Authors
Karimian, Somaye Department of Chemistry - Persian Gulf University, Bushehr, Iran , Tajik, Hassan Young Researchers and Elite Club - Bushehr Branch, Islamic Azad University, Bushehr, Iran
Pages
8
From page
267
To page
274
Abstract
A simple and efficient method for the N-Boc protection of amines using (Boc)2O in the presence of a catalytic amount of silica propyl(N-methyl) imidazolium chloride ([Sipmim]Cl) is introduced. The catalyst was efficient and reusable for this process under solvent-free conditions at ambient temperature. This methodology has several advantages in comparison with currently used methods including high yields, simple workup procedure, short reaction time, and clean and mild reaction conditions.
Keywords
Silica-supported ionic liquid , Silica propyl(N-methyl) imidazolium chloride , N-Boc protection , Tert-butoxycarbonylation , Amine
Journal title
Astroparticle Physics
Serial Year
2016
Record number
2407059
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