Author/Authors :
Anninos Photios نويسنده Laboratory of Medical Physics, Department of Medicine,
School of Health Sciences and Department of Electrical Engineering,
Polytechnic School, Democritus University of Thrace Alexandroupoli
68100, Greece , Adamopoulos Adam نويسنده Laboratory of Medical Physics, Department of Medicine,
School of Health Sciences and Department of Electrical Engineering,
Polytechnic School, Democritus University of Thrace Alexandroupoli
68100, Greece , Kotini Athanasia نويسنده Laboratory of Medical Physics, Department of Medicine,
School of Health Sciences and Department of Electrical Engineering,
Polytechnic School, Democritus University of Thrace Alexandroupoli
68100, Greece , Tsagas Nicolaos نويسنده Laboratory of Medical Physics, Department of Medicine,
School of Health Sciences and Department of Electrical Engineering,
Polytechnic School, Democritus University of Thrace Alexandroupoli
68100, Greece
Abstract :
Background Magnetoencephalography (MEG) is a well-established
noninvasive method for investigating human brain activity. Objectives
The present study aimed at identifying any change in the brain state
after pico- Tesla Transcranial Magnetic Stimulation (pT-TMS) on patients
with multiple sclerosis (MS). Methods A whole-head 122 - channel MEG
system in a magnetically shielded room with low magnetic noise was used.
The study population comprised of 2 male and 8 female volunteers with
MS, with a mean age of 41.3 ± 9.5 years. External magnetic field of
pT-TMS was applied on the above patients with proper field
characteristics (magnetic field amplitude: 1 - 7.5 pT, frequency: the
alpha rhythm of the patient 8 - 13 Hz), obtained prior to the
application of pT-TMS. Results A significant effect was observed with an
increase of frequencies in the range of 2 - 7 Hz among the participants.
The results were statistically significant in 7 out of 10 patients
(70%). Conclusions The pT-TMS has the prospective to be a significant
noninvasive secure and effective means in managing MS symptoms.
