Author/Authors :
Akbarzadeh Baghban Alireza نويسنده , Rahimi Abbas نويسنده Shahid Beheshti University of Medical Sciences, Tehran, Iran , Rashedi Vahid نويسنده Iranian Research Center on Aging, University of Social Welfare and Rehabilitation Sciences, Tehran, IR Iran , Rahbar Soulmaz نويسنده Ph.D. Candidate in Physiotherapy, School of
Rehabilitation, Shahid Beheshti University of Medical Sciences,
Tehran, IR Iran , Naimi Sedigheh Sadat نويسنده Ph.D. in Physiotherapy, Assistant Professor, Physiotherapy
Research Centre, School of Rehabilitation, Shahid Beheshti
University of Medical Sciences, Tehran, IR Iran , Soltani Asghar Reza نويسنده Professor of Physiotherapy, Physiotherapy Research Centre,
School of Rehabilitation, Shahid Beheshti University of Medical
Sciences, Tehran, IR Iran , Tavakkoli Hossein Moein نويسنده Assistant Professor of Endocrinology, Hamadan University
of Medical Sciences, Hamedan, IR Iran
Abstract :
Background Diabetes is a cosmopolitan health problem worldwide,
especially in Asia. It is a metabolic disorder originating from insulin
secretion deficiency, insulin performance or both. When both factors are
involved, abnormal complications may result. Exercise training plays an
important role in controlling diabetic parameters, including
biomechanical variables. Objectives This study aimed at assessing the
effectiveness of exercise on biochemical parameters in patients with
diabetes. Methods This study was a randomized control trial. A total of
30 volunteers met the inclusion criteria and were randomly divided to 2
groups, aerobic and control, by block randomization method. This study
was performed during May to October 2016 in Iran. The intervention
protocol included 24 sessions (8 weeks) of aerobic exercise on the
treadmill with zero slope, 3 days per week for 30 minutes per session.
Intensity of training protocol was 50% to 70% maximum heart rate.
Measurements of biochemical parameters were done before and after the 24
sessions Results There were no significant differences in
anthropometric, gender, age, diabetic history, cardiac ejection
fraction, and biochemical variables (P > 0.05). After 8 weeks,
results were as follows: fasting blood glucose (FBS) (130.92 (45.43)
Mg/dL), glycosylated hemoglobin (HbA1c) (6.62 (1.52) percent),
cholesterol (150.62 (24.07) Mg/dL), triglyceride (119.62 (39.18) Mg/dL),
Low density lipoprotein (LDL) (77.23 (26.73) Mg/dL), and very low
density of lipoprotein (VLDL) (23.92 (7.90) Mg/dL); these were
significantly reduced in the training group (P < 0.05), yet, not
in the control group. Alternatively, high density lipoprotein (HDL)
remained unchanged in the aerobic group (47.85 (17.83) Mg/dL) while it
was increased in the control group (42.07 (8.86) Mg/dL). Also,
C-reactive protein (CRP)) 2.43 (1.03) Mg/L) and microalbumin (12.32
(1.21) Mg) values didn’t change between the 2 groups. Conclusions Eight
weeks of aerobic exercise was shown to be effective in controlling
biochemical parameters. However, longer training duration is needed in
order to modify CRP.
