Author/Authors :
Nariman Shahin نويسنده , Shahriari Ali نويسنده , Khooshideh Maryam نويسنده , Safari Saeid نويسنده Department of Anesthesiology and Critical Care, Iran University of Medical Sciences, Tehran, IR Iran
Abstract :
Background Prenatal mortality and morbidity increase after 40
weeks of gestation. The current study aimed at comparing maternal and
neonatal outcomes between term and postterm pregnancies. Methods The
current prospective cohort study was performed on 1180 singleton,
cephalic fetus, and uncomplicated pregnancy cases admitted for labor.
Pregnant mothers were divided into 3 groups. Group 1 included 750 cases
in 38 to 40 weeks, group 2 included 250 cases in 40 to 41 weeks, and
group 3 included 180 cases in over 41 weeks of gestation. Prenatal
outcomes were recorded as: fetal distress, meconium passage, meconium
aspiration, fetal weight ≥ 4 kg, Apgar score in 1 and 5 minutes,
neonatal intensive care unit (NICU) admission, maternal infection,
postpartum hemorrhage, and the rate of cesarean section. Results There
were significant differences in the rate of fetal distress (P <
0.001), meconium passage (P = 0.001), meconium aspiration syndrome (P
< 0.001), Apgar score ≤ 3 at 1 (P = 0.025) and 5 minutes (P
< 0.001), admission to NICU (P < 0.001), rate of cesarean
section (P < 0.001), and maternal infection (P = 0.001) among the
groups. The frequency of fetal distress was lower in group1 compared
with group 2 (1.6% versus 4.4%; P = 0.011). Also fetal distress was
significantly lower in group 1 than group 3 (1.6% versus 10.9%; P
< 0.001). The meconium passage and meconium aspiration syndrome
were statistically lower in group 1 compared with group 2 (1.6% versus
8%; P < 0.001 for meconium passage, and 0.9% versus 5.6%; P
< 0.001 for meconium aspiration syndrome). Also meconium passage
and meconium aspiration syndrome were significantly lower in group 1
compared with group 3 (1.6% versus 13.9%; P < 0.001 for meconium
passage, and 0.9% versus 10%; P < 0.001 for meconium aspiration
syndrome). The cesarean section was more frequent in group 2 compared
with group 1 (24.8% versus 13.6%; P < 0.001) and in group 3
compared with group 1 (33.3% versus 13.6%, P < 0.001). There was
no significant difference in the mean fetal weight, fetal weight ≥ 4 kg,
and postpartum hemorrhage in females between the 3 groups. Conclusions
Late-term and postterm births are associated with higher rates of fetal
and neonatal morbidity and maternal risks compared to pregnancy
termination before 40 weeks of gestation, and earlier birth induction is
recommended in such cases.