Author/Authors :
Jahani Somayeh نويسنده Infectious Diseases and Tropical Medicine Research Center,Zahedan University of Medical Sciences,Zahedan,Iran , Abkhoo Javad نويسنده Institute of Plant Biotechnology, Center of Agricultural Biotechnology University of Zabol, Zabol, IR Iran
Abstract :
Background Medicinal plants have been known since ancient times,
as an anti-microbial spectrum against microorganisms. The production of
secondary plant metabolites creates an important source of bactericide
and various pharmaceutical drugs. In this study, the antimicrobial
activity of aqueous and ethanolic extracts of the leaves of
Glycyrrhiza glabra, Mentha spicata
and Rosmarinus officinalis was evaluated against
resistant strains of Pseudomonas aeruginosa,
Escherichia coli and Staphylococcus
aureus. Methods Antimicrobial effects of plants were
investigated using a strain of Pseudomonas
aeruginosa, Escherichia coli and
Staphylococcus aureus, at the standard bacterium
laboratory of the Veterinary Department, University of Islamic Azad,
Tehran, Iran. Results Minimum inhibitory concentration (MIC) values
ranged from 6.25 to 100.0 ppm, while Minimum bactericidal concentration
(MBC) ranged from 12.5 to 200 ppm. The ethanol extract of
Glycyrrhiza glabra had the lowest MIC (6.25 ppm),
while the ethanol extract of Rosmarinus officinalis
and Mentha spicata had the highest MIC (100 ppm),
respectively. The MBC of the ethanolic extract of G.
glabra, with the highest bacteria strains, was valuable
against the lowest (12.5 PPM). The MBC of the ethanolic extract of
G. glabra was valuable against the lowest bacteria
strains. Conclusions Our findings showed good antibacterial activity for
G. glabra extract that can be utilized as a treatment
for infections, caused by P. aeruginosa, E.
coli and S. aureus.
