Author/Authors :
Danish Khan Inam نويسنده Assistant Professor (Clinical Microbiology and Infectious
Diseases), Army College of Medical Sciences and Base Hospital, Delhi
Cantt 110010, India , Makkar Anuradha نويسنده Professor and Head Microbiology, Army College of Medical
Sciences and Base Hospital, Delhi Cantt 110010 India , Malik Ajay نويسنده Professor and Head Pathology, Army College of Medical
Sciences and Base Hospital, Delhi Cantt 110010 India , Khan Shazia نويسنده MBBS, MS, Specialist Obstetrics and Gynecology, INHS
Kalyani, Visakapatnam, India , Mehdi Imran نويسنده MBBS, MS, Specialist Ophthalmology, Army Hospital Research
and Referral, Delhi, India , Arif Samreen نويسنده MBBS, MS, Specialist Ophthalmology, Bhopal Memorial
Hospital and Research Centre, Bhopal, India , Aden Durre نويسنده MBBS, MD, Specialist Pathology, Jawaharlal Nehru Medical
College, Aligarh Muslim University, Aligarh, India , Somayaji Prarthana نويسنده PhD, Botanist, Bengaluru, India , Roomi Khushnood نويسنده Chemist and Area Manager, Hafele Saudi Arabia, Mecca,
Saudi Arabia
Abstract :
Introduction Curvularia is an emerging
dematiaceous/melanized/phaeoid hyphomycete causing ocular curvulariosis
including keratomycosis, conjunctivitis, dacryocystitis, sino-orbital
cellulitis, and endophthalmitis. Curvularia ketatomycosis may be
associated with satellite stromal infiltrates, immune rings, Descement’s
folds, iriditis, and endothelial plaque. Surgical trauma followed by
delayed tissue healing may render cornea susceptible to invasion by
exogenous air-dispersed conidia from environment. Cases Presentation
Curvularia lunata keratomycosis occurred in 2
military veterans after phacoemulsification and intraocular lens
implantation without any history of trauma. Topical 5% natamycin was
effective for treatment resulting in minimal residual scar. Complete
recovery and uneventful 1-year follow-up period was observed.
Conclusions Seven out of 30 Curvularia species are
emerging as opportunistic human pathogens from being primary
phytopathogens. With increasing ocular surgeries in the diabetic
populace amongst general population including military veterans, a high
index of clinical and microbiological suspicion is required for optimal
diagnosis of emerging pathogens in post-operative keratomycosis.
