Author/Authors :
Davachi Behrouz نويسنده , Rezaei Alireza نويسنده , Yousefi Zohreh نويسنده , Saied Shohreh نويسنده Resident Fellowship of Gynecology Oncology, Department of
Obstetrics and Gynecology, Ghaem Hospital, School of Medicine,
Mashhad University of Medical Sciences, Mashhad, IR
Iran , Mirzamarjani Fatemeh نويسنده Resident of Obstetrics and Gynecology, Ghaem Hospital,
School of Medicine, Mashhad University of Medical Sciences, Mashhad,
IR Iran
Abstract :
Introduction Choriocarcinoma is a gestational trophoblastic tumor
that mainly affects women of childbearing age and rarely occurs in
postmenopausal women especially following a long latent period from
previous pregnancies. In this case report, we introduce three cases of
postmenopausal choriocarcinoma with different clinical signs and
symptoms. Case Report The first patient was admitted with vaginal wall
metastasis, and the second and third cases with postmenopausal vaginal
bleeding. They were referred to the department of gynecology-oncology at
Ghaem hospital in 2015. One case had stage I and two patients stage III
of the disease. Treatment was initiated with EMA-CO regimen according to
the histopathology of choriocarcinoma in these patients. Complete
remission was achieved with chemotherapy for all three cases. Concusions
The possibility of choriocarcinoma should be considered as a
differential diagnosis in postmenopausal vaginal bleeding and in
postmenopausal women with metestatic lesions.
