Author/Authors :
Rezaianzadeh Abbas نويسنده Department of Epidemiology, Cardiovascular Research Center, Shiraz University of Medical Science , Dehghani Seyedeh Leila نويسنده Department of Public Health, Behbahan Faculty of Medical Sciences, Behbahan, Iran , Nazarzadeh Milad نويسنده , Hassanipour Soheil نويسنده School of Public Health, Shiraz University of Medical Sciences, Shiraz, IR Iran , Mokhtari Ali Mohammad نويسنده Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran , Maghsoudi Ahmad نويسنده Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran , Maharlouei Najmeh نويسنده Health Policy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
Abstract :
Background: Cancer is the leading cause of morbidity and mortality worldwide.
Among gynecological cancers, ovarian cancer is the first cause of cancer-related
deaths. However, only a few studies have evaluated the age-standardized incidence rate
of ovarian cancer in Iranian women. Therefore, the present study aims to systematically
review the age-standardized incidence rate of ovarian cancer in Iran.
Methods: We systematically reviewed the literature that pertained to the incidence
rate of ovarian cancer among Iranian women. In May 2016, we performed searches
of national scientific databases that included SID, Magiran, IranMedex, and IranDoc.
Searches of international databases included PubMed, Scopus, and ScienceDirect. The
retrieved studies were then assessed according to the study’s inclusion criteria.
Results: In this review, we included 14 from 115 articles obtained through searching
national and international databases, grey literature, and hand searching. Based on the
random effects model, the age-standardized incidence rate of ovarian cancer was 3.19
(95% CI: 2.78-3.59).
Conclusion: The study results indicated that the age-standardized incidence rate
of ovarian cancer was considerably low in Iran. The registration methodology normally
used by cancer registries has probably led to an underestimation of the incidence rate
of ovarian cancer among Iranian women. Thus, we recommend the establishment of
cancer registries that cover a broader population.
