Author/Authors :
Afrisham Reza نويسنده Member of Student Research Committee , Shirali Saeed نويسنده Department of Laboratory Sciences, School of Paramedical Sciences, Hyperlipidemia Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran , Ebrahimi Esmaeel نويسنده Department of Biochemistry, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran
Abstract :
Context Diabetes mellitus is the most common endocrine disease
worldwide and its prevalence is increasing. The development of drugs
with fewer side-effects is required when treating this disease. Thus,
the objective of this study was to evaluate the use of traditional
medicine and medicinal plants in this regard. The various mechanisms by
which isolated extracts and herbal compounds exert their effects on
different diabetes mellitus factors was investigated. Evidence
Acquisition Databases such as PubMed, Science Direct, and Web of Science
(from 1990 until the present) were searched, using a detailed list of
terms related to the effects and mechanism of herbal ingredients on
diabetes mellitus complications. Results The presence of secondary
metabolites, such as phenols, flavonoids and alkaloids in plants, have
been used as a source of medication for the treatment of many diseases,
including diabetes mellitus. Following an extensive review of the
literature, it was found that the secondary metabolites of plants have a
wide range of anti-diabetic effects. Conclusions Plant compounds should
be isolated and their effects on diabetes mellitus and its complications
examined in order to treatment for diabetes mellitus.
