Author/Authors :
Vaezi Maryam نويسنده Women’s Reproductive Health Research Centre, Tabriz University of Medical Sciences, Tabriz, Iran. , Ghalehtaki Reza نويسنده 1Department of Community and Preventive Medicine, Tehran University of Medical Sciences, Tehran, Iran , Salarvand Samaneh نويسنده Department of Anatomical and Clinical Pathology, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran , Haeri Hydeh نويسنده Department of Anatomical and Clinical Pathology, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran , Niknejad Nakisa نويسنده Department of Anatomical and Clinical Pathology, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran
Abstract :
[Introduction]Basaloid squamous cell carcinoma (BSCC) of the cervix is an uncommon tumor in female genital tract. The aggressive clinical behavior makes this entity distinguished from other SCC subtypes.[Case Presentation]We described a case of basaloid squamous cell carcinoma in uterine cervix in a 62-year old woman with previous subtotal hysterectomy. Clinical and radiologic examination suggested a 3 cm mass in cervical stump involving left parametrium. She underwent trachelectomy and lymph node dissection followed by adjuvant radiochemotherapy. The light microscopy and immunohistochemistry warranted the basaloid SCC diagnosis that was suspected in pre-operational biopsy. The small, round to oval-shaped cells with scant cytoplasm and hyperchromatic nuclei were positive for cytokeratin AE1/AE3 (CK AE1/AE3) and negative for p63, C-KIT, chromogranin and synaptophysin.[Conclusions]Although this tumor has an aggressive behavior, this is not enough to substantiate that BSCC has a poorer medical outcome as compared to conventional SCC of the cervix.
