Author/Authors :
Fatih Yilmaz Temel نويسنده Department of Radiology, Bezmialem Vakif University, Istanbul, Turkey , Aralasmak Ayse نويسنده Department of Radiology, Bezmialem Vakif University, Istanbul, Turkey , Toprak Huseyin نويسنده Department of Radiology, Bezmialem Vakif University, Istanbul, Turkey , Guler Serhat نويسنده Department of Pediatric Neurology, Bezmialem Vakif University, Istanbul, Turkey , Tuzun Umit نويسنده Department of Radiology, Bezmialem Vakif University, Istanbul, Turkey , Alkan Alpay نويسنده Department of Radiology, Bezmialem Vakif University, Istanbul, Turkey
Abstract :
Heat stroke is the outcome of over heat stress that results in multiorgan dysfunction with a tendency for central nervous system damage. Brain is very sensitive to hyperthermia, especially the cerebellum that has selective vulnerability to heat stroke. There is complex interaction between heat cytotoxicity, coagulation disorder, cytotoxine - mediated systemic inflammatory response causing multiorgan failure, metabolic derangement, and circulatory insufficiency. We reviewed the literature and discussed brain MRI and MR spectroscopy findings of heat stroke, detailed the pathophysiology underlying brain involvement and proposed excitotoxic injury as an alternative mechanism of brain damage in heat stroke.
