Author/Authors :
Amini Elaheh نويسنده , Shariat Mamak نويسنده , Dalili Hosein نويسنده Breast feeding Research Center, Tehran University of Medical Sciences, Tehran, Iran , Niknafs Nikoo نويسنده Neonatologist, Maternal-Fetal and Neonatal Research Center , Nakhostin Maryam نويسنده MD, Breastfeeding Research Center, Vali Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran , Jedari-Attari Saeid نويسنده Neonatologist, Maternal-Fetal and Neonatal Research Center
Abstract :
[Background]Necrotizing enterocolitis (NEC) is a common dangerous gastrointestinal emergency in neonatology, especially in premature infants, which can cause serious problems.[Objectives]This study was conducted to find out whether administration of probiotics could lead to prevention and/or treatment of NEC.[Methods]115 premature newborns weighting 750 - 1500 g or less than 32 weeks’ gestation were checked daily for NEC signs and weight gain and mean day of full feed achievement was recorded.[Results]The incidence of NEC and C-reactive protein (CRP) rise showed a significant difference (P = 0.02) between the two (case and control) groups, but the difference regarding mean duration of oxygen therapy, TPN, full feeding achievement, and hospitalization was not significant.[Conclusions]These results showed positive effects of probiotics on preventing and treating NEC, especially NEC grade 3 in ELBW and VLBW neonates.
