Author/Authors :
Dorri Giv M. نويسنده Radiology and Radiotherapy Department - Faculty of Paramedical - Shahid Beheshti University of Medical Sciences , Bahreini Toosi M. H. نويسنده Medical Physics Research Center - Faculty of Medicine - Mashhad University of Medical Sciences , Aghamiri S. M. R. نويسنده Radiology and Radiotherapy Department - Faculty of Paramedical - Shahid Beheshti University of Medical Sciences , Akbari F. نويسنده Medical Physics Research Center - Faculty of Medicine - Mashhad University of Medical Sciences , Taeb S. نويسنده Department of Radiation Biology and Orotection - Shiraz University of Medical Science
Abstract :
Background: Much research has widely been conducted into thyroid hormones
levels following radiotherapy for breast cancer. Consequently, in this study, we evaluated
to relate the rate of thyroid hormones levels with the dose distribution among
breast cancer patients.
Material and Methods: Thirty patients were treated with 4-field breast cancer
radiotherapy. The dose volume histograms, the volume percentage of the thyroid
absorbing respectively 20, 30, 40 and 50 Gy were then estimated (V20, V30, V40 and
V50) together with the individual average thyroid dose over the whole gland derived
from their computed tomography-based treatment plans. Then, in serum samples triiodothyronine
[T3], thyroxine [T4], thyroid-stimulating hormone [TSH] of the patients
were measured before and after radiotherapy.
Results: There were no significant differences in thyroid hormones levels before
and after radiotherapy for patients with breast cancer (P value > .05).
Conclusion: On the balance, we understood that thyroid stimulating hormones
levels did not change before and after cancer breast radiotherapy.
