Author/Authors :
Hasanzadeh Hadi نويسنده Department of medical physics, Faculty of medicine , Jadidi Majid نويسنده Dept. of Medical Physics, Semnan University of Medical Sciences, Semnan, Iran , Seifi Makrani Danial نويسنده Department of Medical Physics - Faculty of Medical Sciences - Semnan University of Medical Sciences , Allahverdi Pourfallah Tayyeb نويسنده Department of Biochemistry and Biophysics - Faculty of Medicine - Mazandaran University of Medical Sciences , Ghasemi Arash نويسنده Department of Radiology and radiation oncology - Faculty of Medicine - Mazandaran University of Medical Sciences
Abstract :
Esophageal cancer is one of the most common malignancies with a growing occurrence. It presently ranks ninth among the most frequent cancers in the world and the sixth leading cause of death from cancer. For a variety of reasons, the mainstream of patients with esophageal cancer is actually not suitable for Esophagectomy. More than 50% have locally advanced unresectable or metastatic tumors at diagnosis. Other reasons which exclude Esophagectomy include old age, comorbidity or refusal by the patient. For more advanced stages of esophageal cancers, the basis of non-surgical treatment is chemotherapy (CT) or radiotherapy (RT), either alone or in combination as chemoradiotherapy (CRT). The purpose of this study is to summaries and judgmentally analyzes current non-surgical treatments. Although the best treatment for locally advanced esophageal cancer is still being debated, the use of neoadjuvant chemoradiotherapy has gained acceptance.
