Tinosporacordifolia: A Potential Plant with Immunomodulatory Activity

Immunomodulation is a procedure، which can alter the immune system of an organism by interfering its function. Modulation of immune system may result in suppression or stimulation of immunological reactivity. Recently the effect of immunomodulators in the treatment of various diseases is significant. Tinosporacordifolia is a widely used shrub in ayurvedic system of medicine. It is reported to benefit the immune system in a variety of ways. The medicinal properties incorporated with this plant are anti-diabetic، hypolipidemic، anti-neoplastic، anti-oxidant، anti-inflammatory، immunomodulatory، cognitive، adaptogenic، aphrodisiac، cardioprotective and hepatoprotective effect. Many compounds belonging to different classes such as alkaloids، diterpenoids، phenol، aliphatic compounds and polysaccharides have been isolated from this plant. But it is not well known that which of these compounds are responsible for various activities. Therefore، it needs further exploration of its components، pharmacological action and mechanism of action. This review presents a detail survey of literature on immunomodulatory properties of T.cordifolia. The main aim of the survey is to reinforce scientific reconfirmation of its immunological activities and human studies.