Author/Authors :
Abbas, Qamar Department of Biology - Kongju National University, Gongju, Chungnam 314-701, Republic of Korea , Saleem, Muhammad Department of Chemistry - Kongju National University, Gongju, Republic of Korea , Phull, Abdul Rehman Department of Biology - Kongju National University, Gongju, Chungnam 314-701, Republic of Korea , Rafiq, Muhammad Department of Biology - Kongju National University, Gongju, Chungnam 314-701, Republic of Korea , Hassan, Mubashir Department of Biology - Kongju National University, Gongju, Chungnam 314-701, Republic of Korea , Lee, Ki-Hwan Department of Chemistry - Kongju National University, Gongju, Republic of Korea , Seo, Sung-Yum Department of Biology - Kongju National University, Gongju, Chungnam 314-701, Republic of Korea
Abstract :
Herbal nanoparticles gain lot of attention because of their pharmaceutical importance. The
present study reports the eco-friendly synthesis, characterization and their tyrosinase activity
of silver nanoparticles (AgNPs) using aqueous extract of Bidens frondosa. The appearance
of brown color indicated the formation of B. frondosa AgNPs. The Formation of AgNPs was
confirmed by UV–Vis spectroscopy, FTIR, FESEM and EDS analysis. The formation of herbal
AgNPs of size ranging 20-70 nm further was assured by energy dispersive X-ray spectroscopy
(EDS) and field emission scanning electron microscopy (FESEM). The mushroom tyrosinase
inhibitory activity of synthesized AgNPs was evaluated. Nanoparticles were found to have
significant higher tyrosinase inhibitory activity compared to control. The IC50 values of crude
extract, AgNP and Kojic acid were found to be 9, 15, and 2.37 μg/mL, respectively. AgNPs
of B. frondosa may be considered as potential candidate for the production of medical and
cosmetic products.
Keywords :
Tyrosinase Activity , Silver Nanoparticles , Medicinal Plants , Bidens frondosa
