Author/Authors :
Rahimzadeh, Poupak Pain Research Center - Iran University of Medical Sciences, Tehran, Iran , Imani, Farnad Pain Research Center - Iran University of Medical Sciences, Tehran, Iran , Sayarifard, Azadeh Center for Academic and Health Policy - Tehran University of Medical Sciences , Sayarifard, Sara Iran University of Medical Sciences, Tehran, Iran , Faiz, Hamid Reza Endometriosis and gynecologic disorders Research Center - Iran University of Medical Sciences, Tehran, Iran
Abstract :
Background: Postoperative pain is one of the major problems in patients with femoral or hip fracture. Current
study investigates the effect of 0.2% and 0.3% bupivacaine in ultrasound-guided fascia iliaca compartment
block (FICB) on postoperative pain.
Methods: This randomized clinical trial study was conducted in Rasoul Akram Hospital of Iran University of
Medical Sciences. Forty-eight patients with femoral or hip fractures who were candidates for surgery underwent
FICB, divided into two groups receiving bupivacaine in 0.2% and 0.3% concentrations. Pain was evaluated with
Visual Analog Scale (VAS) at times 2, 6, 12, 24, and 48 hours after surgery. Need for opioids, nausea and vomiting
after surgery, patients’ satisfaction with pain control and motor block were also recorded. T-test or Mann-
Whitney U test and Repeated measure ANOVA was used for analysis.
Results: Pain score after surgery was significantly lower in groups receiving 0.3% than the group receiving
0.2% concentration. Patients’ satisfaction with pain control in 0.2% group was significantly higher (p=0.04).
Time to analgesic onset in both groups had no significant differences (p=0.5). The incidence of nausea and vomiting
(p=0.5) and opioid consumption (p=0.1) between the two groups showed no significant difference.
Conclusion: In femoral or hip fracture, bupivacaine with 0.3% concentration in fascia iliaca compartment
block can cause lower pain score compared to bupivacaine with 0.2% concentration, but patients’ satisfaction
with pain control and severity of motor block is higher in bupivacaine 0.2%.