Simultaneous Determination of Ascorbic Acid, Uric Acid and Acetaminophen on a Glassy Carbon Electrode Coated with a Novel Single Walled Carbon Nanotubes/ Chitosan/ MCM-41 Composite

The present work demonstrates that simultaneous determination of ascorbic acid (AA), uric acid (UA) and acetaminophen (ACT) can be performed on a novel single walled carbon nanotubes (SWCNTs), chitosan (CHIT) and MCM-41 composite modified glassy carbon electrode (SWCNTs-CHIT-MCM-41/GCE). The electro-oxidations of AA, UA and ACT were investigated by using differential pulse voltammetry (DPV), chronoamperometry (CA) and electrochemical impedance spectroscopy (EIS) methods. Under optimum conditions application of DPV method showed that the linear relationship between oxidation peak current and concentration of AA, UA and ACT were 1-160 μM, 0.1-24 μM and 0.1-21 μM with detection limits of 0.41, 0.04 and 0.03 μM, respectively