Selective Determination of Norepinephrine at SAOS/MWCNT/MCPE: A Voltammetric Study

A simultaneous determination of Norepinephrine (NE) using Sodium alpha olefin sulfonate/multi-walled carbon nanotube modified carbon paste electrode was developed by voltammetric techniques. The modified electrode shows excellent electrocatalytic activity towards the oxidation of NE in phosphate buffer solution (PBS) of pH 6.8. The electrochemical studies of scan rate, reveals the overall electrode process for NE was controlled by adsorption and for Epinephrine was diffusion. The pH studies confirm that an equal number of protons and electrons were involved in the electrochemical detection of NE. The lower limit of detection of NE and EP was discussed. The interference studies showed that the modified electrode exhibits excellent selectivity in the presence of large excess of Epinephrine (EP). The separation of the oxidation peak potentials for NE–EP was about 0.203 V. This peak difference was large enough to determine NE and EP individually and simultaneously. This method offers a simple and easy approach to selectively detect various bioactive molecules.