Author/Authors :
SEIFI, Sharareh Medical Oncology Department - National Research Institute of TB and Lung Disease - Masih Daneshvari Hospital , ASVADI KERMANI, Iraj Hematology and Oncology Research Centre - Tabriz University of Medical Sciences , DOLATKHAH , Roya Hematology and Oncology Research Centre - Tabriz University of Medical Sciences , ASVADI KER-MANI, Atabak Hematology and Oncology Research Centre - Tabriz University of Medical Sciences , SAKHINIA, Ebrahim Biochemistry Department, Faculty of Medicine, Tabriz University of Medical Sciences , ASGARZADEH, Mohammad Biochemistry Department, Faculty of Medicine, Tabriz University of Medical Sciences , DASTGIRI, Saeed Hematology and Oncology Research Centre - Tabriz University of Medical Sciences , EBRAHIMI, Ayoub Hematology and Oncology Research Centre - Tabriz University of Medical Sciences , ASGHARI HAGGI, Arezou Hematology and Oncology Research Centre - Tabriz University of Medical Sciences , NADRI, Mahsa Dept. of Microbiology - Arak Azad University , ASVADI KERMANI, Touraj Hematology and Oncology Research Centre - Tabriz University of Medical Sciences
Abstract :
Background: Human papilloma virus causes benign and malignant abnormalities in different part of the body. The link between high risk types of HPV and some anogenital and aerodigestive tract cancer is well established. Oral HPV infection plays a role in developing oropharyngeal squamous cell carcinoma. We studied the prevalence of oral HPV in healthy individuals and its relative risk factors.
Methods: Saliva samples of 114 healthy subjects were collected for HPV DNA analysis. Volunteers completed ques-tionnaires and signed a written consent. For data analysis descriptive statistic, chi square test and odds ratio was used.
Results: The frequency of oral HPV in healthy individuals was 6.1 %( seven participant).The most frequent type was HPV-18 in five of them.HPV-6 and HPV-66 each was detected in one case. Relation of oral HPV positivity to demo-graphic features and risk factors was not statistically significant.
Conclusions: The prevalence of oral HPV infection in our community is the same as many other communities of developing countries, stressing that HPV-18 were the dominant type.
Keywords :
Human Papilloma Virus , HPV , Oral Cancer , Saliva
