Author/Authors :
HOSEINI, Fatemeh Sadat Dept. of Anatomy - School of Medicine - Tehran University of Medical Sciences, Tehran, Iran , ESLAMI, Mohammad Dept. of Population - Family and School Health - Ministry of Health and Medical Education, Tehran, Iran , ABBASI, Mohammad Family Planning Office - Gilan University of Medical Sciences, Rasht, Iran , NOROOZI FASHKHAMI, Fatemeh Family Planning Office - Gilan University of Medical Sciences, Rasht, Iran , BESHARATI, Soheila Family Planning Office - Gilan University of Medical Sciences, Rasht, Iran
Abstract :
We aimed to compare acceptability of Levonorgestrel with the Yuzpe regimen among Iranian women based on their side-effects and resulting changes in the amount and pattern of menses.Five hundred twenty nine participants aged 15-49 having regular menses and one act of unprotected intercourse within 72 h were included in the double-blind, controlled trial in 2006-2007 and randomly assigned into LNG (n=263) and HD (n=266) groups, receiving Levonorgestrel 0.75 mg given 12 h apart and ethinyl estradiol 100 μg plus 0.5 mg Levonorgestrel 0.5 mg repeated after 12 h, respectively.The participants receiving Levonorgestrel experienced significantly lower side-effects in the case of nausea, vomiting, and dizziness (P<0.05). The changes occurred in the amount and pattern of menses were the same for both groups (P>0.05). No significant difference was observed between the efficiencies of the treatments.Significantly lower side-effects of Levonorgestrel can be considered as greater acceptability and translated to higher efficiency.
Keywords :
Levonorgestrel , Yuzpe regimen , Emergency contraception , Side-effects
