Author/Authors :
Ghazi, Ali Research Institute for Endocrine Sciences - Taleghani General Hospital - Shahid Beheshti University of Medical Sciences - Tehran , Boustani, Iranpour Department of Surgery - Kasra General Hospital - Tehran , Amouzegar, Atieh Research Institute for Endocrine Sciences - Taleghani General Hospital - Shahid Beheshti University of Medical Sciences - Tehran , Attarian, Hamid Department of Internal Medicin - Taleghani Hospital - Shahid Beheshti University of Medical Sciences - Tehran , Pourafkari, Marina Department of Radiology - Taleghani Hospital - Shahid Beheshti University of Medical Sciences - Tehran , Nejad Gashti, Hossein Department of Internal Medicine - Hashemi Nejad Hospital - Iran University of Medical Sciences - Tehran , Sabetian, Taher Department of Obstetrics and Gynechology - Kasra General Hospital - Tehran , Tirgari, Farrokh Department of Pathology - Imam Khomeini Hospital - Tehran University of Medical Sciences - Tehran , Ghazi, Siavash Department of Internal Medicin - Taleghani Hospital - Shahid Beheshti University of Medical Sciences - Tehran , Kovacs, Kalman Department of Laboratory Medicine - Saint Michael’s Hospital - University of Toronto - Toronto Ontario - Canada
Abstract :
Parathyroid hormone-related protein producing pancreatic neuroendocrine tumors have been infrequently reported. Herein, we report a case of an Iranian woman who had such a tumor during pregnancy, and gave birth to a female neonate with esophago-tracheal fistula and imperforated anus. Hypercalcemia was diagnosed at postpartum because of elevated serum calcium levels in the neonate and neurologic deterioration of the mother. Extensive literature review revealed 42 cases with pancreatic neuroendocrine tumors and hypercalcaemia. The clinical and laboratory findings of such patients are reviewed in this manuscript.
