Author/Authors :
Ghafoori, Mahyar Department of Radiology - Hazrat Rasoul Akram Hospital - School of Medicine - Iran University of Medical Sciences, Tehran, Iran , Alavi, Manijeh Deputy of Research and Technology - Ministry of Health and Medical Education, Tehran, Iran , Shakiba, Madjid Advanced Diagnostic and Interventional Radiology Research Center (ADIR) - Tehran University of Medical Sciences, Tehran, Iran , Hoseini, Kamal 4Department of Urology - School of Medicine - Hazrat Rasoul Akram Hospital - Iran University of Medical Sciences, Tehran, Iran
Abstract :
Background: In prostate cancer, detection of seminal vesicle involvement is important because it influences the treatment planning and
prognosis of the patients. Objectives: The objective of this study was to determine the value of prostate MRI with endorectal coil in the detection of seminal vesicle
involvement in patients with prostate cancer. Patients and Methods: A total number of 238 biopsy-proven prostate cancer patients were examined by 1.5 Tesla MRI with a combination of pelvic and endorectal coils to detect seminal vesicle involvement. After radical prostatectomy, the MRI results were compared with
pathology results. Results: Seminal vesicle involvement was detected in 67 (28.1%) patients. Pathology confirmed the involvement of seminal vesicles by
prostate cancer in 63 patients. In two patients, seminal vesicle involvement was diagnosed by pathology but not detected by MRI. The
sensitivity was 0.97 [95% confidence interval = 0.89-0.99], the specificity was 0.98 [95% confidence interval = 0.94-0.99], the positive
predictive value was 0.94 [95% confidence interval = 0.85-0.98], and the negative predictive value was 0.99 [95% confidence interval = 0.96-
0.99]. Conclusion: MRI with endorectal coil is a valuable imaging technique with suitable accuracy in detecting seminal vesicle involvement in
prostate cancer.
Keywords :
Prostate Cancer , Seminal Vesicles , Staging , MRI
